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Key Points-Infectious Diseases
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4 Posts
James
Senior Member
Topics: 14
Posts: 127
Posted 12/13/11 - 02:00 AM
#1
Meningococcal prophylaxis must be given to close contacts of the patient with meningococcal meningitis. The drug of choice is Rifampin for 2 days. A good alternative is Ciprofloxacin - single dose but this cannot be given to patients under the age of 17.
James
Senior Member
Topics: 14
Posts: 127
Posted 12/13/11 - 02:03 AM
#2
Not all patients with pneumonias have to be admitted.
The following should be however considered for admission:
HIV positive.
Dyspneic
Elderly
Poorly compliant.
Those who have other reasons for admission e.g. Dehydration, vomiting etc.
those with a poor cardio respiratory reserve.
ICU admission is needed for those who are Tachypneic (>30/min) or HR > 120 or hypercapneic >45 or those with acidosis pH</= 7.3.
James
Senior Member
Topics: 14
Posts: 127
Posted 12/13/11 - 02:08 AM
#3
Men <35 on the other hand are commonly infected with GC and Chlamydia thus investigate but empirically treat with Ceftriaxone(for GC) 125 mg x 1 dose IM + Doxy(for Chlamydia) 100 bid X10 days or use single drug therapy with one dose Azithromycin-2gm or Ofloxacin x 10 days.
James
Senior Member
Topics: 14
Posts: 127
Posted 12/13/11 - 02:09 AM
#4
Nucleoside analogues: ZZLSD : Zidovudine, Zalcitabine, Lamivudine, Stavudine and Didanosine
Non nucleoside analogues: (seems like they are named after 2 states- Delaware and Nevada)-Delavirdine and Nevirapine
Protease inhibitors : RINS : Ritonavir, Indinavir, Nelfinavir and Saquanavir
Side effects
AZT: Anemia, Asthenia, Granulocytopenia, Macrocytosis
DDI: (DD~PP): Pancreatitis & peripheral neuropathy
Stavudine: Peripheral neuropathy
Zalcitabine: peripheral neuropathy, Oral ulcers
Lamivudine: well tolerated
Delavirdine: Skin rash
Nevirapine : RASH
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